Error 8020: Error reading comm device
As described by Microsoft,
this error message is the result of a defective serial port device driver. It should be resolved by by obtaining an updated device driver from your serial port or USB adapter manufacturer
Some USB devices that emulate serial ports employ the usbser.sys driver. Unfortunately, the version of usbser.sys included with Windows 10 is defective, resulting DXLab applications reporting an 8020 error when they attempt to communicate with such devices.